Market Update Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis Health” or “the Company”) MARKET UPDATE It has come to the attention of the Company that allegations have been made through social media that certain shareholders have been approached by a “large US private equity firm” to acquire all of the Ascendis Health shares. The board of directors of Ascendis Health wish to inform shareholders that it has not received any correspondence that would constitute a firm intention to make an offer to Ascendis Health shareholders and that it has not entered into discussions around a process that may result in one being forthcoming in the short- to medium-term. Shareholders will be advised in the manner required in terms of the Listings Requirements of the JSE and the provisions of the Companies Act, 2008 should it either enter into discussions relating to an offer or should it receive a firm intention to make an offer. 03 September 2021 Bryanston Sponsor Questco Corporate Advisory Proprietary Limited Date: 03-09-2021 05:06:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.